Consecutive nucleophilic substitution and aza Diels–Alder reaction—an efficient strategy to functionalized 2,2′-bipyridines

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• 作者：Dmitry N. Kozhevnikov ; Valery N. Kozhevnikov ; Anton M. Prokhorov ; Maria M. Ustinova ; Vladimir L. Rusinov ; Oleg N. Chupakhin ; Grigory G. Aleksandrov and Burkhard Kö ; nig
• 刊名：Tetrahedron Letters
• 出版年：2006
• 出版时间：6 February 2006
• 年：2006
• 卷：47
• 期：6
• 页码：869-872
• 全文大小：147 K

文摘

An efficient strategy for the synthesis of functionalized 2,2′-bipyridines is reported. The strategy is based on readily available 3-pyridyl-1,2,4-triazine 4-oxides and uses a reaction sequence of nucleophilic substitution of hydrogen and aza Diels–Alder reaction.