Controlled release of alendronate from nitrogen-doped mesoporous carbon
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- 作者：Dipendu Sahaa ; dsaha@mail.widener.edu" class="auth_mail" title="E-mail the corresponding author ; depends@gmail.com" class="auth_mail" title="E-mail the corresponding author ; Amanda Spurria ; Jihua Chenb ; Dale K. Hensleyb
- 关键词：Nitrogen doping ; Mesoporous carbon ; Alendronate ; Osteoporosis ; Controlled release
- 刊名：Microporous and Mesoporous Materials
- 出版年：2016
- 出版时间：15 July 2016
- 年：2016
- 卷：229
- 期：Complete
- 页码：8-13
- 全文大小：1687 K
文摘
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Nitrogen-doped carbon was synthesized with BET surface area 1066 m2/g.
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Alendronate was release in pH = 1.2, 4.5, 6.8 and 7.4 at 37 °C.
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Only 20% of alendronate from carbon was released in pH = 1.2.
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All alendronate was released in pH = 1.2 in 30 min only.