Two sRNA libraries were constructed and sequenced with or without LPS infection.
A total of 218 conserved miRNAs and 106 putative novel miRNAs were identified.
113 miRNAs were found to be differentially expressed between two libraries.
Selected miRNA expression profiles were consistent between sequencing and RT-qPCR data.
This is the first comprehensive study of miRNAs for immune tissues in Megalobrama amblycephala.