Molecular characterization and immunological response analysis of toll-like receptors from the blunt snout bream (Megalobrama amblycephala)

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• 作者：Rui-Fang Lai^a ; ^{lairuifang@webmail.hzau.edu.cn} ; Ivan Jakovlić^a ; ^c ; ^{ivanjakovlic@yahoo.com} ; Han Liu^a ; ^{lifegood1986@126.com} ; Fan-Bin Zhan^a ; ^{1203248258@qq.com} ; Jin Wei^a ; ^{1161104243@qq.com} ; Wei-Min Wang^a ; ^b ; ^{wangwm@mail.hzau.edu.cn}
• 关键词：TLR ; Fish ; Expression ; Aeromonas hydrophila
• 刊名：Developmental & Comparative Immunology
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：67
• 期：Complete
• 页码：471-475
• 全文大小：1534 K
• 卷排序：67

文摘

14 TLR genes were characterized and analyzed in Megalobrama amblycephala. Phylogenetic tree of MaTLRs obviously showed the existence of six TLR families. All MaTLRs were constitutively expressed with variations in eight tested tissues. The expression profiles of MaTLRs were analyzed after A. hydrophila infection. Results indicated that most of MaTLRs might involve in the immune responses.