APOEε4 impacts up-regulation of brain-derived neurotrophic factor after a six-month stretch and aerobic exercise intervention in mild cognitively impaired elderly African Americans: A pilot study
Older adult men but not women demonstrate exercise-induced increases in VO2Max. Exercise-induced up-regulation of BDNF varies by APOE genotype. Muted BDNF response to physiological adaptations may explain ε4-related AD risk.