Inverse linear associations between liver aminotransferases and incident cardiovascular disease risk: The PREVEND study
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- 作者：Setor K. Kunutsora ; b ; skk31@cantab.net" class="auth_mail" title="E-mail the corresponding author ; Stephan J.L. Bakkerc ; d ; Jenny E. Kootstra-Rose ; Hans Blokzijlf ; Ronald T. Gansevoortc ; Robin P.F. Dullaartg
- 关键词：Alanine aminotransferase ; Aspartate aminotransferase ; Cardiovascular disease ; Risk factor ; Risk prediction
- 刊名：Atherosclerosis
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：243
- 期：1
- 页码：138-147
- 全文大小：885 K
文摘
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ALT and AST are each approximately log-linearly associated with CVD risk.
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The associations are inverse and independent of conventional CVD risk factors.
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The associations hold true across the normal ranges of the aminotransferases.
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ALT or AST is unlikely to improve CVD risk assessment in the general population.