N(α)-histogram analysis of the ventricular fibrillation ECG-signal as predictor of countershock success
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文摘
Previous work has suggested that the heart in ventricular fibrillation can be defibrillated more easily if the ECG shows higher mean-frequencies or higher absolute voltages. We investigated whether information on defibrillation success is encoded in the random behaviour of the ECG-signals during fibrillation in a porcine model of cardiac arrest. To estimate the degree of randomness we used N(α)-histograms, which have been used to characterize turbulent flows or to denoise astrophysical data. We found that width of N(α)-histograms can serve as predictors for defibrillation success. The width decreases the more random the ECG-signal behaves. In our setting, the probability to find values αi>2.5 is dramatically increased by application of the vasopressor vasopressin (and conversely decreased for values αi<2.5). Even 10–12 min after fibrillation, vasopressin returns N(α)-histograms to the form they show 40 s after initiation of ventricular fibrillation. Publisher: Elsevier Science Language of Publication: English Item Identifier: S0960-0779(99)00028-4 Publication Type: Article ISSN: 0960-0779 Cited by:
  1. Hamprecht, Fred A.; Achleitner, Ulrich; Krismer, Anette C.; Lindner, Karl H.; Wenzel, Volker; Strohmenger, Hans-Ulrich; Thiel, Walter; van Gunsteren, Wilfred F.; Amann, Anton,""Fibrillation power, an alternative method of ECG spectral analysis for prediction of countershock success in a porcine model of ventricular fibrillation""Resuscitation2001pp. 287-296
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  2. Amann, Anton; Achleitner, Ulrich; Antretter, Herwig; Bonatti, Johannes O.; Krismer, Anette C.; Lindner, Karl H.; Rieder, Josef; Wenzel, Volker; Voelckel, Wolfgang G.; Strohmenger, Hans-Ulrich,""Analysing ventricular fibrillation ECG-signals and predicting defibrillation success during cardiopulmonary resuscitation employing N(a)-histograms1""Resuscitation2001pp. 77-85
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Footnotes:
  1. Financial disclosure: The authors have no possible conflicts of interest, sources of financial support, corporate involvement, patent holdings, etc. in association with the topic of the present manuscript.

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