Loss of electrical anisotropy is an unrecognized feature of dystrophic muscle that may serve as a convenient index of disease status
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- 作者：Seward B. Rutkovea ; srutkove@bidmc.harvard.edu" class="auth_mail" title="E-mail the corresponding author ; Jim S. Wub ; Craig Zaidmanc ; Kush Kapurd ; Sung Yima ; Amy Pasternakd ; Lavanya Madabusid ; Heather Szelagd ; Tim Harringtond ; Jia Lia ; Adam Pachecka ; Basil T. Darrasd
- 关键词：Duchenne muscular dystrophy ; Anisotropy ; Impedance ; Biomarker
- 刊名：Clinical Neurophysiology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：127
- 期：12
- 页码：3546-3551
- 全文大小：959 K
文摘
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Surface electrical impedance measurements can reveal the anisotropic character of muscle.
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The anisotropic characteristics of muscle are disrupted in Duchenne muscular dystrophy (DMD).
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Electrical anisotropy can serve as a biomarker for evaluation of muscle condition in DMD.