Management of hot flashes in women with breast cancer receiving ovarian function suppression

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• 作者：Roberto A. Leon-Ferre^a ; Neil Majithia^b ; Charles L. Loprinzi^a ; ^{cloprinzi@mayo.edu}
• 关键词：Hot flashes ; Hot flushes ; Vasomotor symptoms ; Tamoxifen ; Breast cancer ; Estrogen
• 刊名：Cancer Treatment Reviews
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：52
• 期：Complete
• 页码：82-90
• 全文大小：390 K
• 卷排序：52

文摘

Vasomotor symptoms are a frequent adverse effect of estrogen deprivation. Hormone replacement therapy is not an ideal option for breast cancer patients. Non-pharmacologic measures may be enough to control mild vasomotor symptoms. SSRI/SNRI or anticonvulsants should be first-line in moderate-to-severe symptoms. In women taking tamoxifen, potent CYP2D6 inhibitors should be avoided.