Clinical features and outcomes of interstitial lung disease in anti-Jo-1 positive antisynthetase syndrome
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- 作者：Ana C. Zamoraa ; 1 ; Sumedh S. Hoskotea ; 1 ; Beatriz Abascal-Boladob ; Darin Whitec ; Christian W. Coxc ; Jay H. Ryua ; Teng Mouaa ; moua.teng@mayo.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：Antisynthetase syndrome ; Jo-1 antibody ; Antinuclear antibody ; Interstitial lung disease ; Dermatomyositis ; Polymyositis
- 刊名：Respiratory Medicine
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：118
- 期：Complete
- 页码：39-45
- 全文大小：406 K
文摘
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Anti-jo-1 antisynthetase syndrome is commonly associated with interstitial lung disease.
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In this large single-center cohort, the most common presenting radiologic pattern was NSIP.
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Usual interstitial pattern on CT or pathology was not associated with worse survival.
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Male gender and low DLCO were independent predictors of poorer outcomes.