Neuropeptide Y expression confers benzo[a]pyrene induced anxiolytic like behavioral response during early adolescence period of male Wistar rats

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• 作者：Saroj Kumar Das ; Manorama Patri ; ^{mpatri@ravenshawuniversity.ac.in}
• 关键词：Benzo[a]pyrene ; Anxiety ; Neuropeptide Y ; Calcium ; Oxidative stress ; Serotonin
• 刊名：Neuropeptides
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：61
• 期：Complete
• 页码：23-30
• 全文大小：804 K
• 卷排序：61

文摘

Benzo[a]pyrene (B[a]P) induces anxiolytic like behavioral response. B[a]P induces neuropeptide Y (NPY) over expression in brain regions. NPY over expression confers anxiolytic like behavioral response following B[a]P administration. B[a]P induced NPY over expression leads to orexigenic effect. B[a]P induced NPY overexpression in brain causes increase in intracellular Ca2 + level.