A simple and effective enrichment process of the antiproliferative lignan arctigenin based on the endogenous enzymatic hydrolysis of Serratula tinctoria and Arctium lappa fruits
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- 作者：Anna Só ; lyomvá ; rya ; b ; Zsolt Mervaic ; Gergő Tó ; thd ; Á ; gnes Evelin Ressa ; Bé ; la Noszá ; ld ; Ibolya Molná ; r-Perle ; Korné ; lia Baghyc ; Ilona Kovalszkyc ; Imre Boldizsá ; ra ; boldizsarimi@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Isolation ; Lignan ; Arctigenin ; Arctium ; Serratula ; Microtubule
- 刊名：Process Biochemistry
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：50
- 期：12
- 页码：2281-2288
- 全文大小：839 K
文摘
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A simple, effective method was developed to prepare the precious lignan arctigenin.
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Method was based on the enzymatic hydrolysis of S. tinctoria and A. lappa fruits.
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Enzyme-hydrolyzed fruit of S. tinctoria is a new and rich source of arctigenin.
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Arctigenin was proved to inhibit the microtubular system of SW480 carcinoma cells.