Arf6 mediates Schwann cell differentiation and myelination
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- 作者：Tomohiro Toriia ; Yuki Miyamotoa ; Masahiro Yamamotoc ; Katsuya Ohbuchic ; Hideki Tsumurab ; Kazuko Kawaharaa ; Akito Tanouea ; Hiroyuki Sakagamid ; Junji Yamauchia ; e ; yamauchi-j@ncchd.go.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Arf6 ; Schwann cell ; Nerve ; Myelination ; Signaling
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2015
- 出版时间：25 September 2015
- 年：2015
- 卷：465
- 期：3
- 页码：450-457
- 全文大小：1789 K
文摘
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Arf6 knockdown in Schwann cells decreases myelin marker expression.
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Schwann cell-specific Arf6 knockdown mice decrease the marker expression.
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Arf6 knockdown in vivo exhibits reduced myelin thickness.
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Arf6 knockdown in vivo exhibits decreased myelination-related signaling.
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Arf6 is involved in the regulation of myelin sheath formation.