Comparative study on the effects of a new antifungal lotion (Artemisia sieberi

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• 作者：A.R. Khosravi ; H. Shokri ; M.H. Darabi ; A. Kashani ; P. Mansouri ; A. Naser
• 关键词：Pityriasis versicolor ; Malassezia furfur ; Mycoderm ; Clotrimazole ; Artemisia sieberi
• 刊名：Journal de Mycologie Médicale / Journal of Medical Mycology
• 出版年：2009
• 出版时间：March 2009
• 年：2009
• 卷：19
• 期：1
• 页码：17-21
• 全文大小：242 K

文摘

Summary

Objective

To determine the efficacy of Mycoderm lotion (Artemisia sieberi essential oil) in treating Pityriasis versicolor and comparing its effects with clotromazole lotion.

Material and methods

Sixty-eight patients, 34 males and 34 females, were enrolled in this study. The disease was confirmed by standard mycological method; direct microscopic examination. The patients randomly divided into two groups, which treated with Mycoderm and clotrimazole lotions twice daily for two weeks and then followed up for two weeks.

Results

The results showed 71 % improvement in clotrimazole group and 91.9 % in Mycoderm group after two weeks of the treatment, representing significant statistical difference between two groups (p < 0.05). The rate of improvement was shown 67.7 % and 100 % in clotrimazole and Mycoderm groups after four weeks of the treatment, respectively (p < 0.001). Moreover, at the end of treatment, 51.6 % and 70.3 % of the clotrimazole and Mycoderm groups were cured, respectively.

Conclusion

It is concluded that Mycoderm lotion, as a new antifungal agent, could be used in treating patients with Pityriasis versicolor into the future.