2-Arylbenzothiazoles labeled with [CpRe/99mTc(CO)3] and evaluated as β-amyloid imaging probes
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- 作者：Jianhua Jiaa ; Kaixiang Zhoua ; Jiapei Daib ; Boli Liua ; Mengchao Cuia ; cmc@bnu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Alzheimer's disease ; β-amyloid ; Affinity ; SPECT imaging
- 刊名：European Journal of Medicinal Chemistry
- 出版年：2016
- 出版时间：29 November 2016
- 年：2016
- 卷：124
- 期：Complete
- 页码：763-772
- 全文大小：2500 K
文摘
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99mTc/Re-labeled 2-arylbenzothiazoles were synthesized and evaluated as Aβ probes.
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[99mTc]4h labeled Aβ deposits in the blood vessels on brain section of AD patient.
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20">[99mTc]4h may be used to detect Aβ related disease other than AD.