Trichosporon asahii sepsis in a patient with pediatric malignancy

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• 作者：Aslinur Ozkaya-Parlakay^a ; Eda Karadag-Oncel^a ; ^{dredakaradag@gmail.com" class="auth_mail" title="E-mail the corresponding author} ; Ali Bulent Cengiz^a ; Ates Kara^a ; Atilla Yigit^b ; Safak Gucer^c ; Deniz Gur^d
• 关键词：Child ; Sepsis ; Trichosporon asahii
• 刊名：Journal of Microbiology, Immunology and Infection
• 出版年：2016
• 出版时间：February 2016
• 年：2016
• 卷：49
• 期：1
• 页码：146-149
• 全文大小：540 K

文摘

Trichosporon asahii is a rare opportunistic infection, especially in children, causing a life-threatening fungal infection underlying hematologic malignancies. Predisposing factors for infection with this pathogen are immunodeficiency including underlying malignancy, organ transplantation, extensive burns, human immunodeficiency virus infection, corticosteroid therapy, prosthetic valve surgery, and peritoneal dialysis. In the literature, a breakthrough under caspofungin, micafungin therapy is reported. In this article we report on a 16-year-old patient with Ewing sarcoma who had T. asahii sepsis. The patient died although he had been receiving caspofungin for less than 3 months and amphotericin B therapy for 3 days. A postmortem study of conchal tissues revealed T. asahii and mucormycosis histopathologically, and blood culture grew T. asahii.