Genetic variants at 18q11.2 and 8q24 identified by genome-wide association studies were not associated with pulmonary tuberculosis risk in Chinese population
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- 作者：Ruifen Miaoa ; 1 ; ruifenmiao@126.com" class="auth_mail" title="E-mail the corresponding author ; Haibo Geb ; 1 ; Lin Xub ; Zhaoping Suna ; Chen Lia ; Rong Wanga ; Songning Dinga ; Chen Yanga ; Fei Xua ; frankxufei@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Tuberculosis ; Polymorphism ; ASAP1 ; GWAS
- 刊名：Infection, Genetics and Evolution
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：40
- 期：Complete
- 页码：214-218
- 全文大小：417 K
文摘
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GWAS identified TB risk related loci at 8q24 and 18q11.2 in Europeans and Africans.
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No associations were observed for 8q24 and 18q11.2 with TB in Chinese populations.
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The known TB related loci are population-specific and are not important in Chinese.