A joint action of aptamers and gold nanoparticles chemically trapped on a glassy carbon support for the electrochemical sensing of ofloxacin

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• 作者：Sanaz Pilehvar^aAuthor Vitae ; Christine Reinemann^bAuthor Vitae ; Fabio Bottari^aAuthor Vitae ; Els Vanderleyden^cAuthor Vitae ; Sandra Van Vlierberghe^a ; ^cAuthor Vitae ; Ronny Blust^dAuthor Vitae ; Beate Strehlitz^bAuthor Vitae ; Karolien De Wael^a ; ^{karolien.dewael@uantwerpen.be}Author Vitae
• 关键词：Ofloxacin ; Au nanoparticles ; Electrochemical aptasensor ; Covalent attachment ; Water quality ; Environmental monitoring
• 刊名：Sensors and Actuators B: Chemical
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：240
• 期：Complete
• 页码：1024-1035
• 全文大小：2215 K
• 卷排序：240

文摘

A new electrochemical aptasensing strategy is developed based on chemically entrapped AuNPs onto a glassy carbon electrode (GCE) surface for the detection of ofloxacin. The covalently anchored AuNPs on the GCE surface were used as electronic bridges, to enhance the probe immobilization capacity and to increase the long-term stability of the attached aptamers. The sensor exhibited high specificity toward ofloxacin with a limit of detection (LOD) of 1 nM. The developed aptasensing method was successfully applied to determine ofloxacin in tap water and effluent sewage plant water samples.