• 作者：Heidi J. Larson ; PhD^a ; ^b ; ¹ ; ^{heidi.larson@lshtm.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Alexandre de Figueiredo ; MSc^c ; ¹ ; ^{alexandre.de-figueiredo07@imperial.ac.uk" class="auth_mail" title="E-mail the corresponding author} ; Zhao Xiahong ; BSc^d ; William S. Schulz ; MSc^a ; Pierre Verger ; PhD^e ; ^f ; ^g ; ^h ; Iain G. Johnston ; PhDⁱ ; Alex R. Cook ; PhD^d ; ^j ; Nick S. Jones ; PhD^c
• 关键词：Vaccine confidence ; Vaccine safety ; Attitudes ; Global immunization ; Hierarchical regression
• 刊名：EBioMedicine
• 出版年：2016
• 出版时间：October 2016
• 年：2016
• 卷：12
• 期：Complete
• 页码：295-301
• 全文大小：573 K

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Overall vaccine confidence is positive, though responses differ between countries.

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The European region has the lowest confidence in vaccine safety with France the least confident globally.

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Bangladesh, Ecuador, and Iran reported highest agreement that vaccines are important.

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Azerbaijan, Russia, and Italy reported most skepticism around vaccine importance.

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Education increases confidence in vaccine importance and effectiveness but not safety.

This global survey builds on previous studies of vaccines' perceived importance, safety, effectiveness, and religious compatibility. The worldwide survey investigates attitudes towards vaccines on an unprecedented scale, interviewing 65,819 respondents across 67 countries. This can help inform public health agendas by highlighting national and regional variations in attitudes towards vaccines; for example, that the European region is the least confident region towards vaccine safety. One pattern shared by diverse countries worldwide is a worrying gap between high confidence in vaccine importance yet lower confidence in safety, identifying at-risk countries whose vaccine acceptance may be more precarious than previously thought. Meanwhile, factors such as religion, which past research shows to be crucial in some sub-populations, display no consistent pattern at the global scale, emphasizing the importance for future research of understanding the local drivers of vaccine confidence in more detail.