Autoantibody recognition mechanisms of MUC1
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- 作者：J.C. Phillips jcphillips8@comcast.net
- 关键词：Autoantibody ; Cancer ; Early detection ; Mucin ; Glycosylation
- 刊名：Physica A: Statistical Mechanics and its Applications
- 出版年：2017
- 出版时间：1 March 2017
- 年：2017
- 卷：469
- 期：Complete
- 页码：244-249
- 全文大小：636 K
- 卷排序：469
文摘
Cost-effective early cancer biomarkers are based on p53 and mucin epitopes. Mucin molecular structure is dominated by partially glycosylated repeats. Analysis of hydrogen-bonded ββ strand propensities explains observed sensitivities.