Autoantibody to scaffold attachment factor B (SAFB): A novel connective tissue disease-related autoantibody associated with interstitial lung disease

详细信息    查看全文

• 作者：Akiko Takeuchi^a ; Takashi Matsushita^a ; Kenzo Kaji^a ; Yoshinobu Okamoto^a ; Masahide Yasui^b ; Masayoshi Hirata^c ; Naoto Oishi^d ; Akira Higashi^e ; Mariko Seishima^f ; Tomoya Asano^g ; ¹ ; Manabu Fujimoto^a ; ^h ; Masataka Kuwanaⁱ ; Kazuhiko Takehara^a ; Yasuhito Hamaguchi^a ; ^{yasuhito@med.kanazawa-u.ac.jp}
• 关键词：Anti-SAFB Ab ; Anti-nuclear Ab ; Interstitial lung disease ; Raynaud's phenomenon
• 刊名：Journal of Autoimmunity
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：76
• 期：Complete
• 页码：101-107
• 全文大小：881 K
• 卷排序：76

文摘

Autoantibody (autoAb) against scaffold attachment factor B (SAFB) is a novel connective tissue disease-related autoAb. Anti-SAFB Ab is detected in a small number of patients with systemic sclerosis and/or idiopathic inflammatory myopathy. Interstitial lung disease was observed in patients with anti-SAFB Ab as a relatively common manifestation. Patients with anti-SAFB Ab have Raynaud’s phenomenon and nail fold punctate hemorrhage at a constant rate.