Structural study of the effects of mutations in proteins to identify the molecular basis of the loss of local structural fluidity leading to the onset of autoimmune diseases

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• 作者：Ananya Ali ; Semanti Ghosh ; Angshuman Bagchi ; ^{angshu@klyuniv.ac.in} ; ^{angshuman_bagchi@yahoo.com}
• 关键词：PPI ; Autoimmune diseases ; Relative solvent accessibility ; Mutation ; Lyaunov exponent
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：26 February 2017
• 年：2017
• 卷：484
• 期：1
• 页码：165-170
• 全文大小：1053 K
• 卷排序：484

文摘

Protein-Protein Interaction. Changes in Relative Solvent Accessibility (RSA). Amino acid conversion matrix. Polymorphic mutations. Disease causing mutations.