• 作者：Marina Carrasco Llatas^a ; ^{fernandoymarina@ono.com} ; Celia Ló ; pez Mollá ; ^a ; Ramó ; n Balaguer Garcí ; a^a ; Marí ; a José ; Ferrer Ramí ; rez^a ; Fernando Guallart Domé ; nech^a ; José ; Enrique Estellé ; s Ferriol^a ; Sergio Ferná ; ndez Martí ; nez^b ; José ; Dalmau Galofre^a
• 关键词：C&aacute ; ncer de hipofaringe ; Tratamiento ; Supervivencia
• 刊名：Acta Otorrinolaringol¨®gica Espa?ola
• 出版年：2009
• 出版时间：February 2009
• 年：2009
• 卷：60
• 期：1
• 页码：3-8
• 全文大小：127 K

Objective

Hypopharyngeal carcinoma is an aggressive malignancy usually diagnosed at a late state, thereby resulting in overall poor prognosis and low survival rates for these patients. The purpose of this study is to present the progress and outcomes of patients treated for hypopharyngeal carcinoma at our department.

Material and method

We retrospectively reviewed 89 patients who had been diagnosed with hypopharygeal carcinoma between 1980 and 2005. Most of the tumours were advanced (T3 and T4) and 73 % showed palpable regional metastases at presentation.

Results

The five-year survival rate was 40.7 % . The overall incidence of distant metastases and subsequent primary neoplasms was 7.5 % and 23.5 % , respectively.

Conclusions

Hypopharyngeal cancer is still the one with the worst prognosis in the head and neck area. The poor survival rate seems to be related primarily to advanced stage disease at presentation and particularly to the status of cervical lymph-node metastases.