Efficient synthesis of novel tetrahydropyrrolo[3¡ä,4¡ä:3,4]pyrrolo[2,1-a] isoquinoline derivatives via a simple and convenient MCR in aqueous micellar system
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- 作者：Shyamal Mondal ; Arindam Maity ; Rupankar Paira ; Maitreyee Banerjee ; Yogesh P. Bharitkar ; Abhijit Hazra ; Sukdeb Banerjee ; Nirup B. Mondal
- 关键词：Multi-component reaction ; 1 ; 3-Dipolar cycloaddition ; Pyrrolopyrroloisoquinoline ; Aqueous micellar system
- 刊名：Tetrahedron Letters
- 出版年：2012
- 出版时间：14 November, 2012
- 年：2012
- 卷：53
- 期：46
- 页码：6288-6291
- 全文大小：521 K
文摘
A simple and efficient one-pot three component synthesis of tetrahydropyrrolo[3¡ä,4¡ä:3,4]pyrrolo[2,1-a]isoquinoline-9,11-dione derivatives has been achieved from variously substituted isoquinolines, 2-bromo acetophenone and N-aryl maleimide derivatives in an aqueous micellar medium. The synthesis represents an environmentally benign alternative to classical methods.