Resisting the Urge to Act: DREADDs Modifying Habits

详细信息    查看全文

• 作者：Mark A.G. Eldridge¹ ; ^{Mark.Eldridge@nih.gov} ; Barry J. Richmond¹ ; ^{Barry.Richmond@nih.gov}
• 刊名：Trends in Neurosciences
• 出版年：2017
• 出版时间：February 2017
• 年：2017
• 卷：40
• 期：2
• 页码：61-62
• 全文大小：222 K
• 卷排序：40

文摘

Recently, Meyer and Bucci used chemogenetic technology – artificial excitatory and inhibitory receptors – to modulate neuronal activity in two connected brain regions in opposite directions simultaneously. This innovative manipulation revealed that the two regions studied, orbitofrontal cortex and nucleus accumbens, are not sequentially dependent during contextual decision-making.