A polysaccharide with 40 % mono-O-methylated monosaccharides from the bark of Cola cordifolia (Sterculiaceae), a medicinal tree from Mali (West Africa)
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- 作者：Adiaratou Togola ; Knut Hå ; kon Naess ; Drissa Diallo ; Hilde Barsett ; Terje E. Michaelsen ; Berit Smestad Paulsen
- 关键词：Cola cordifolia ; Polysaccharide ; Native methylated monosaccharides ; Structure
- 刊名：Carbohydrate Polymers
- 出版年：2008
- 出版时间：19 July 2008
- 年：2008
- 卷：73
- 期：2
- 页码：280-288
- 全文大小：160 K
文摘
A novel type polysaccharide was isolated from the bark of Cola cordifolia (Cav.) R. Br. (Sterculiaceae), a plant used in traditional medicine in Mali (West Africa). The polysaccharide was isolated from the water extract by ion exchange chromatography. Structural studies showed that this was a highly complex new type polysaccharide containing 20 % of 2,3- and 2,4-linked rhamnose, 24 % of galacturonic acid mostly 4-linked, 15 % of terminal, 3- and 4-linked galactose, 20 % of terminal and 3-linked 2-O-methyl galactose, 18 % of 4-O-methyl glucuronic acid which was also terminally linked, and 2 % of terminal 2-O-methyl fucose. This paper reports in addition to structural features, physical property and complement fixating activity using human serum as target of this novel polysaccharide. This is a first report of a plant polysaccharide containing such a diverse composition and quantity of natively methylated monosaccharides.