• 作者：F.S. Lozano S¨¢nchez ; J.R. March Garc¨ªa ; E. Carrasco Carrasco ; J.M. Lobos Bejarano ; investigadores del grupo VITAL
• 关键词：Enfermedad arterial perifé ; rica ; Claudicació ; n intermitente ; Í ; ndice tobillo-brazo ; Cuestionario mejora marcha ; Calidad de vida ; Cuestionario EuroQol
• 刊名：Angiolog¨ªa
• 出版年：2013
• 出版时间：July-August, 2013
• 年：2013
• 卷：65
• 期：4
• 页码：131-140
• 全文大小：833 K

Introduction

Intermittent claudication (IC) is a very prevalent condition in Western countries including the population of Spain. However, little is known about the medical profile and quality of life (QoL) of the IC in Spain.

Aim

To determine the clinical characteristics and QoL in a large sample of Spanish patients with IC.

Material and methods

An observational, prospective, cross sectional and multicentre study was performed between October 2010 and January 2011, with 625 investigators recruiting 1,641 consecutive patients with claudication. The sample was divided into two groups: m>a)m> patients evaluated by vascular surgeons (VS) (n = 920), and m>b)m> patients evaluated by general practitioners (GP) (n = 721). Demographical and clinical characteristics, analytical findings (glucose levels and lipid metabolism) and the Ankle-Brachial Index (ABI) were recorded. Each patient included in the study also filled in two questionnaires: the Walking impairment Questionnaire (WIQ) and the European Quality of Life-5 Dimensions (EQ-5D).

Results

The population mean age was 68.3 ¡À 9.4 years; in 75.3 % of the cases the patients were males. The presence of risk cardiovascular factors (49.5 % of diabetes; 76.9 % of hypertension and 65.3 % of dyslipemia) and comorbid conditions (in particular, cardiovascular diseases) were high. The mean ABI of the series was 0.66 ¡À 0.19. Patients in the VS group had more severe IC than patients from GP Group (ABI = 0.63 vs ABI = 0.71, m>Pm><.001). WIQ scores obtained were: m>a)m> walking distance = 35.09 ¡À 25.73; m>b)m> walking speed = 36.18 ¡À 22.83, and m>c)m> stair-climbing capacity = 41.76 ¡À 27.62. We only found significant statistical differences in walking distance between the VS Group and GP Group. The global EQ-5D score was 0,57 ¡À 0,21. No significant differences were observed between the VS and GP groups.

Conclusions

Spanish patients with IC showed three characteristics: high cardiovascular risk, limited ability to tolerate exercise, and reduction in the quality of their life. There are differences between groups; compared to general practitioners, vascular surgeons treated patients with more advanced disease.