In vitro evidence for gut hormone stimulation release and dipeptidyl-peptidase IV inhibitory activity of protein hydrolysate obtained from cuttlefish (Sepia officinalis) viscera
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- 作者：Benoit Cudenneca ; 1 ; benoit.cudennec@univ-lille1.fr" class="auth_mail" title="E-mail the corresponding author ; Rafik Baltib ; 1 ; Rozenn Ravalleca ; Juliette Carona ; Ali Bougatefb ; Pascal Dhulstera ; Naï ; ma Nedjara
- 关键词：Bioactive peptides ; DPP-IV inhibitors ; Incretin effect ; GLP-1 ; CCK ; Diabetes
- 刊名：Food Research International
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：78
- 期：Complete
- 页码：238-245
- 全文大小：613 K
文摘
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In Tunisia, cephalopods industry processing generates wastes causing environmental pollution and commercial loss.
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Cuttlefish hydrolysates were able to stimulate gut hormone release in enteroendocrine cells and to inhibit DPP-IV activity.
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Hydrolysates bioactivities assessed after GI digestion were enhanced by the action of proteases compared with raw byproduct.
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This cuttlefish byproduct hydrolysate will be useful in obesity and T2D management research.