A Landscape of Pharmacogenomic Interactions in Cancer
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- 作者：Francesco Iorio
- 刊名：Cell
- 出版年：2016
- 出版时间：28 July 2016
- 年：2016
- 卷：166
- 期：3
- 页码：740-754
- 全文大小：2759 K
文摘
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- <p id="p0010">We integrate heterogeneous molecular data of 11,289 tumors and 1,001 cell linesp>
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- <p id="p0015">We measure the response of 1,001 cancer cell lines to 265 anti-cancer drugsp>
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- <p id="p0020">We uncover numerous oncogenic aberrations that sensitize to an anti-cancer drugp>
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- <p id="p0025">Our study forms a resource to identify therapeutic options for cancer sub-populationsp>