刊名:Biochimica et Biophysica Acta (BBA) - General Subjects
出版年:2017
出版时间:January 2017
年:2017
卷:1861
期:1
页码:3289-3299
全文大小:2011 K
卷排序:1861
文摘
Developed two specific aptamers against human heart type fatty acid binding protein. Aptamer-protein interactions were analyzed by a combinatorial approach. Aptamer-protein interactions were accompanied by change in their conformations. Aptamers with low Kd exhibited high ionic interactions. Aptamers with high Kd exhibit more synergistic conformational change.