Dinuclear arene ruthenium thiolato complexes with fluorous side-chains
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- 作者：David Stí ; bala ; Tina Riedelb ; Paul J. Dysonb ; Georg Sü ; ss-Finka ; Bruno Therriena ;
- 关键词：Bioorganometallic chemistry ; Arene ruthenium complexes ; Dinuclear complexes ; Thiolato ligands ; Fluorine chemistry ; Hyperthermia
- 刊名：Inorganica Chimica Acta
- 出版年：2016
- 出版时间：1 April 2016
- 年：2016
- 卷：444
- 期：Complete
- 页码：51-55
- 全文大小：869 K
文摘
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Synthesis and characterization of dinuclear trithiolato arene ruthenium complexes.
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Incorporation of fluorous side-chains increases the lipophilicity.
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The dinuclear complexes show high cytotoxicity to cancerous cells.
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The dinuclear complexes exhibit some selectivity for cancerous over healthy cells.