Inflammatory bowel disease is associated with hidradenitis suppurativa: Results from a multicenter cross-sectional study

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• 作者：Inge E. Deckers ; MD ; PhD^a ; Farida Benhadou ; MD^b ; Marjolein J. Koldijk ; MD^c ; Veronique del Marmol ; MD ; PhD^b ; Barbara Horvá ; th ; MD ; PhD^c ; Jurr Boer ; MD ; PhD^d ; Hessel H. van der Zee ; MD ; PhD^a ; Errol P. Prens ; MD ; PhD^a ; ^{e.prens@erasmusmc.nl}
• 关键词：acne inversa ; Crohn's disease ; ulcerative colitis ; comorbidity ; epidemiology ; risk factor ; prevalence ; association
• 刊名：Journal of the American Academy of Dermatology
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：76
• 期：1
• 页码：49-53
• 全文大小：161 K
• 卷排序：76

文摘

Hidradenitis suppurativa (HS) is often associated with inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis). However, the prevalence of IBD in HS patients is unknown.ObjectiveTo determine the prevalence of IBD in HS patients, and determine if patients with HS and IBD have a distinct HS phenotype.MethodsFor this multicenter, cross-sectional study, HS patients were asked during their first consultation if they had IBD. The diagnosis of IBD was checked in the medical files, and clinical characteristics were collected.ResultsIBD had a prevalence of 3.3% (95% CI 2.3-4.4) in 1076 HS patients. The prevalence of Crohn's disease was 2.5% (95% CI 1.6-3.4) and the prevalence of ulcerative colitis was 0.8% (95% CI 0.3-1.4). HS-IBD patients were less frequently obese (13.9% vs 31.2%, P = .04) than HS-only patients, but there were no differences in gender, family history of HS, disease severity, body areas affected by HS, or smoking status.LimitationsThe prevalence might be underestimated since HS patients might still develop IBD.ConclusionThe prevalence of IBD in HS patients (3.3%) is 4-8 times higher than the prevalence in the general northern European population (0.41%-0.74%), however HS-IBD patients do not have a distinct HS phenotype.