Social dysfunction after pediatric traumatic brain injury: A translational perspective
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- 作者：Nicholas P. Ryana ; b ; nicholas.ryan@mcri.edu.au" class="auth_mail" title="E-mail the corresponding author ; Cathy Catroppaa ; b ; c ; cathy.catroppa@mcri.edu.au" class="auth_mail" title="E-mail the corresponding author ; Celia Godfreya ; celia.godfrey@mcri.edu.au" class="auth_mail" title="E-mail the corresponding author ; Linda J. Noble-Haeussleind ; linda.noble@ucsf.edu" class="auth_mail" title="E-mail the corresponding author ; Sandy R. Shultze ; sandy.shultz@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author ; Terence J. O&rsquo ; Briene ; obrientj@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author ; Vicki Andersona ; b ; c ; vicki.anderson@rch.org.au" class="auth_mail" title="E-mail the corresponding author ; Bridgette D. Semplee ; Bridgette.Semple@unimelb.edu.au" class="auth_mail" title="E-mail the corresponding author
- 关键词：CCI ; controlled cortical impact ; CT ; computed tomography ; DTI ; diffusion tensor imaging ; FPI ; fluid-percussion injury ; HMSC ; Heuristic Model of Social Competence ; MRI ; magnetic resonance imaging ; pTBI ; pediatric traumatic brain injury ; p21 ; post-natal day 21 ; QoL ; quality of life ; SBN ; social brain network ; SWI ; susceptibility-weighted imaging ; TBI ; traumatic brain injury ; ToM ; Theory of Mind
- 刊名：Neuroscience & Biobehavioral Reviews
- 出版年：2016
- 出版时间：May 2016
- 年：2016
- 卷：64
- 期：Complete
- 页码：196-214
- 全文大小：2609 K
文摘
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Social dysfunction is common yet understudied after traumatic brain injury (TBI).
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Injury-related and environmental factors modulate social outcomes after TBI.
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Rodent models of TBI reveal clinically-relevant deficits in social interactions.
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Parallel experimental and clinical research may delineate underlying mechanisms.