刊名:The Journal of Steroid Biochemistry and Molecular Biology
出版年:2017
出版时间:March 2017
年:2017
卷:167
期:Complete
页码:98-105
全文大小:1060 K
卷排序:167
文摘
Syncytiotrophoblasts shows higher expression of the steroideogenic enzymes than cytotrophoblasts. Short time calcitriol treatment increases the CYP11A1, CYP19A1 and 3β-HSDI expression in human placenta. CYP17A1 and 17β-HSD3 gene are expressed in low levels in human placenta. Calcitriol effects are dependent on the treatment time and the differentiation process of trophoblast cells.