文摘
Novel method to quantify the Ca2+ fluxes involved in excitation contraction coupling The method is based on analysis of action potential clamp data by mathematical model. Method was tested against synthetic data and applied to reveal Ca2+ fluxes in trout. In trout, NCXrev is the main transmembrane Ca2+ influx pathway. In trout, 50% of Ca2+ transient is attributable to CICR from SR.