Helix B surface peptide attenuates diabetic cardiomyopathy via AMPK-dependent autophagy

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• 作者：Chen Lin^a ; Mingming Zhang^a ; Yingmei Zhang^b ; Kejian Yang^a ; Jianqiang Hu^a ; Rui Si^a ; Guoyong Zhang^a ; Beilei Gao^a ; Xiang Li^a ; Chennian Xu^a ; Congye Li^a ; Qimeng Hao^c ; Wenyi Guo^a ; ^{docguo196@163.com}
• 关键词：Diabetic cardiomyopathy ; Helix B surface peptide ; Apoptosis ; Autophagy
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：22 January 2017
• 年：2017
• 卷：482
• 期：4
• 页码：665-671
• 全文大小：2456 K
• 卷排序：482

文摘

HBSP could improve cardiac function in mice with diabetic cardiomyopathy. HBSP exerted protective effects through restoration of autophagy. Activation of AMPK might be involved.