Chylomicrons are large, triglyceride-rich lipoproteins formed in the intestine after a meal.
Fasting healthy people have no chylomicrons in the blood serum.
Most of monogenic diseases causing hyper- or hypochylomicronemia that can be diagnosed by clinical chemistry and genetic studies.
Hyperchylomicronemia is a major risk factor of pancreatitis
The first gene therapy approved in Europe is directed to LPL deficiency, the main cause of type I hyperlipidemia.