• 作者：Maria del Carmen Vazquez-Pedrazuela^a ; Maria-Belen Canton-Alvarez^b ; ^{cerrapasa@yahoo.es} ; Maria del Carmen de la Fuente-Hontañ ; on^c ; Angel Soloaga-Morales^d ; Jose-Maria Collazos-del Castillo^d ; Roberto Sertal-Parcero^d
• 关键词：Ancianos ; Dé ; ficit de vitamina B12 ; Dé ; ficit de á ; cido fó ; lico
• 刊名：Revista Espa?ola de Geriatr¨ªa y Gerontolog¨ªa
• 出版年：2012
• 出版时间：November-December, 2012
• 年：2012
• 卷：47
• 期：6
• 页码：259-261
• 全文大小：152 K

Introduction

The aim of this study is to establish the prevalence of vitamin B12 and folic acid deficiency in the population of 65 years and over in semi-urban and rural area, as well as investigating the risk factors, and the determining factors of this deficiency in this population and its relationship with the prevalence of concomitant cardiovascular and cognitive diseases.

Materials and methods

A cross-sectrionall study conducted in the Geriatrics Outpatients in the period between 2008 and 2010. Demographic, clinical and laboratory were collected at 3 different times.A bivariate analysis was performed with lack of vitamin B12 and folic acid, as the outcome variables.

Results

Vitamin B12 defieciency was found in 16.5 % of the sample, and no folic acid deficiency. A strong association was found with vitamin B12 deficiency and cardiac and cerebrovascular diseases, vascular risk factors and drugs administered in prevention of cardiac events and ischaemic stroke.

Conclusions

There was a higher prevalence of vitamin B12 deficiency in the elderly population in the catchment area of Medina del Campo compared to that found in the literature, but not so with the isolated deficiency of folic acid.