A copper (I or II)/diethylphosphite catalytic system for base-free additive dimerization of alkynes

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• 作者：Inna G. Trostyanskaya ; Irina P. Beletskaya ; ^{beletska@org.chem.msu.ru}
• 关键词：Catalysis ; Copper salts and oxides ; Diethylphosphite ; Alkynes ; 1 ; 3-enynes ; 1 ; 4-diphenylbuta-1 ; 3-diyne
• 刊名：Tetrahedron
• 出版年：2017
• 出版时间：12 January 2017
• 年：2017
• 卷：73
• 期：2
• 页码：148-153
• 全文大小：922 K
• 卷排序：73

文摘

Copper (I) or copper (II) salts and oxides promote regioselective head-to-head additive dimerization of aromatic and aliphatic terminal alkynes in the presence a catalytic amount of diethylphosphite. The reaction proceeds under ambient conditions without any added base with the formation of 1,4-disubstituted 1,3-enynes with the E isomer as major product in good to excellent yields. A plausible mechanism for additive dimerization of terminal alkynes is proposed.