Relationship between seizure frequency and number of neuronal and non-neuronal cells in the hippocampus throughout the life of rats with epilepsy
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- 作者：Glauber Menezes Lopima ; Diego Vannucci Camposa ; Sé ; rgio Gomes da Silvab ; e ; Alexandre Aparecido de Almeidaa ; Roberto Lentc ; Esper Abrã ; o Cavalheirod ; Ricardo Mario Aridaa ; arida.nexp@epm.br" class="auth_mail" title="E-mail the corresponding author
- 关键词：SE ; status epilepticus ; SRS ; spontaneous recurrent seizures ; PBS ; phosphate-buffered saline ; PB ; phosphate-buffered ; DAPI ; 4&prime ; -6-diamidino-2-phenylindole dihydrochloride ; NeuN ; neuron-specific nuclear protein ; MRI ; magnetic resonance imaging ; DG ; dentate gyrus ; GFAP ; glial fibrillary acidic protein
- 刊名：Brain Research
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：1634
- 期：Complete
- 页码：179-186
- 全文大小：749 K
文摘
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Seizure frequency varies in animals with epilepsy according to the period of life.
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Recurrent spontaneous seizures reduce the number of hippocampal neuronal cells.
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The total number of neuronal cells was negatively correlated with seizure frequency.