刊名:Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
出版年:2017
出版时间:February 2017
年:2017
卷:1862
期:2
页码:246-254
全文大小:1270 K
卷排序:1862
文摘
Schistosomal-derived lipids induce M2 polarization of macrophages. LPC is the main component within schistosomal lipid extract that triggers macrophage M2 polarization. Schistosomal-derived LPC induces PPARγ increased expression in macrophages. M2 polarization of macrophages triggered by schistosomal-derived LPC occurs through PPARγ dependent mechanism.