Ovarian cancer stem-like cells differentiate into endothelial cells and participate in tumor angiogenesis through autocrine CCL5 signaling
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- 作者：Shu Tanga ; 1 ; Tong Xianga ; b ; 1 ; Shuo Huanga ; Jie Zhoua ; Zhongyu Wanga ; Rongkai Xiec ; Haixia Longa ; longhaixialhx@163.com" class="auth_mail" title="E-mail the corresponding author ; Bo Zhua ; b.davis.zhu@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Ovarian cancer ; Cancer stem cell ; CCL5 ; Angiogenesis ; Endothelial cell differentiation
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：28 June 2016
- 年：2016
- 卷：376
- 期：1
- 页码：137-147
- 全文大小：3021 K
文摘
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Ovarian CSLCs could differentiate into ECs.
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ECs differentiation of ovarian CSLCs is mediated through autocrine CCL5.
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NF-κB and STAT3 pathways control CCL5-mediated ECs differentiation of CSLCs.