Inhibition of CDK1 activity by sumoylation
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- 作者：Yuxuan Xiaoa ; Benjamin Lucasa ; Elana Molchoa ; Tania Schiffa ; Margarita Vigodnera ; b ; vigodner@yu.edu" class="auth_mail" title="E-mail the corresponding author
- 关键词：CDK1 ; Phosphorylation ; Sumoylation ; Ginkgolic acid ; H2O2 ; siRNA
- 刊名：Biochemical and Biophysical Research Communications
- 出版年：2016
- 出版时间：16 September 2016
- 年：2016
- 卷：478
- 期：2
- 页码：919-923
- 全文大小：622 K
文摘
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Inhibition of sumoylation by different means increases the activity of CDK1.
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Inactive CDK1 isoform is enriched in the SUMO pool-down fraction.
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Inhibition of sumoylation affects the sumoylatyion status of CDK1-interacting proteins.