A multiplexed three-dimensional paper-based electrochemical impedance device for simultaneous label-free affinity sensing of total and glycated haemoglobin: The potential of using a specific single-frequency value for analysis
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- 作者：Yuwadee Boonyasita ; Orawon Chailapakulb ; Wanida Laiwattanapaisalc ; Wanida.L@chula.ac.th" class="auth_mail" title="E-mail the corresponding author
- 关键词：Glycated haemoglobin ; Three-dimensional paper-based electrochemical impedance device ; 3-Aminophenylboronic acid ; Haptoglobin ; Eggshell membrane ; Label-free electrochemical detection
- 刊名：Analytica Chimica Acta
- 出版年：2016
- 出版时间：14 September 2016
- 年：2016
- 卷：936
- 期：Complete
- 页码：1-11
- 全文大小：1860 K
文摘
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A cost-effective 3D-PEID was developed for label-free impedimetric affinity sensing of total and glycated haemoglobin.
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Determination of the optimal binding frequency facilitates fast impedance measurements using a single frequency.
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Hp and APBA are recognition elements for selective binding of total and glycated haemoglobin, respectively.
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The proposed system meets the clinical requirements for glycaemic assessment in diabetic patients.