Analysis of the protective effects of the α₂/δ subunit of voltage-gated Ca²⁺ channels in brain injury

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• 作者：Tae Yeon Kim ; ^{taeyeonkim@brain.riken.jp} ; Kimie Niimi ; Eiki Takahashi
• 关键词：Gabapentin ; Rolling Nagoya ; Brain injury ; Cav.2.1 ; Cav.2.1α1 subunit ; Cav.2.1α2/δ subunit
• 刊名：Brain Research
• 出版年：2017
• 出版时间：15 January 2017
• 年：2017
• 卷：1655
• 期：Complete
• 页码：138-144
• 全文大小：917 K
• 卷排序：1655

文摘

Injecting gabapentin decreased the cryogenic lesion size. Gabapentin suppressed the p38MAPK signaling cascade by disturbing Cav2.1 signaling. Injecting gabapentin attenuated reactive astrocyte activity. Injecting gabapentin attenuated neuronal degeneration.