Functional mesoporous silica nanoparticles (MSNs) for highly controllable drug release and synergistic therapy
详细信息 查看全文
- 作者：Yin-Jia Cheng ; Xuan Zeng ; Dong-Bing Cheng ; Xiao-Ding Xu ; xd-xu@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xian-Zheng Zhang ; Ren-Xi Zhuo ; Feng He ; hefeng@whu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Synergistic cancer therapy ; Mesoporous silica nanoparticles ; Disulfide bond ; Multifunctional peptide
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 September 2016
- 年：2016
- 卷：145
- 期：Complete
- 页码：217-225
- 全文大小：2772 K
文摘
- •
Two functional peptides (TCPP and TPP) were designed and synthesized.
- •
Highly controllable MSNs were prepared by using TCPP and TPP as gatekeepers.
- •
The newly developed MSNs show a remarkable synergistic anticancer effect.