Changes in body weight and body mass index among psychiatric patients receiving lithium, valproate, or topiramate: An open-label, nonrandomized chart review
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- 作者：Chengappa ; K.N. Roy ; Chalasani ; L. ; Brar ; Jaspreet S. ; Parepally ; H. ; Houck ; Patricia ; Levine ; Joseph
- 关键词：mood stabilizers ; topiramate ; lithium ; valproate ; obesity ; body weight ; body mass index ; bipolar disorder
- 刊名：Clinical Therapeutics
- 出版年：2002
- 出版时间：October, 2002
- 年：2002
- 卷：24
- 期：10
- 页码：1576-1584
- 全文大小：611 K
文摘
Background: Subsets of psychiatric patients gain excess body weight while receiving mood-stabilizing agents such as lithium carbonate or valproate sodium. Patients who gain excess weight may discontinue therapy, with severe consequences. Among the newer anticonvulsant agents, topiramate is a candidate agent for bipolar disorder and is associated with weight loss when used as adjunctive treatment.