Vertical order of DPPC multilayer enhanced by cholesterol-induced ripple-to-liquid ordered (LO) phase transition: Synchrotron X-ray reflectivity study

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• 作者：Suho Lee ; Dae-Woong Jeong ; Myung Chul Choi ; ^{mcchoi@kaist.ac.kr}
• 关键词：Cholesterol ; Lipid membrane ; Phase transition ; Vertical structures ; Synchrotron X-ray reflectivity
• 刊名：Current Applied Physics
• 出版年：2017
• 出版时间：March 2017
• 年：2017
• 卷：17
• 期：3
• 页码：392-397
• 全文大小：875 K
• 卷排序：17

文摘

Structure of DPPC-cholesterol multilayer was investigated using synchrotron X-ray reflectivity with customized X-ray cell. Lamellar spacing and fluorescence image of DPPC-cholesterol multilayer reveals phase transition under 10% cholesterol. The full width at half maximum (FWHM) data shows significant increase in membrane vertical order from 3 to 10% cholesterol. Cholesterol induced ripple-to-liquid ordered (LO) phase transition enhances vertical order of DPPC multilayer.