An Efficient Catalytic Stereoselective Route to a Key Intermediate for the Synthesis of the Long-Lived PGI₂ Analog ZK 96480 (Cicaprost^TM)

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• 作者：Corey ; E.J. ; Helal ; Christopher J.
• 刊名：Tetrahedron Letters
• 出版年：1997
• 出版时间：October 27, 1997
• 年：1997
• 卷：38
• 期：43
• 页码：7511-7514
• 全文大小：491 K

文摘

An expeditious and stereoselective synthesis of a key chiral intermediate (2) for the synthesis of the therapeutically useful PGI₂ analog Cicaprost^TM is described. © 1997 Elsevier Science Ltd.