A HClO-specific near-infrared fluorescent probe for determination of Myeloperoxidase activity and imaging mitochondrial HClO in living cells
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- 作者：Fengshou Tiana ; 1 ; Yan Jiab ; c ; 1 ; Yanan Zhanga ; b ; c ; Wei Songd ; Guangjiu Zhaob ; c ; Zongjin Qub ; c ; Chunyan Lia ; b ; c ; Yahong Chena ; Peng Lib ; c ; pengl@dicp.ac.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Near-infrared ; ClO&minus ; /MPO detection ; Bio-imaging ; Real-time monitoring ; Mitochondria targeting
- 刊名：Biosensors and Bioelectronics
- 出版年：2016
- 出版时间：15 December 2016
- 年：2016
- 卷：86
- 期：Complete
- 页码：68-74
- 全文大小：2323 K
文摘
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Cy7-NphS is a near-infrared probe for HClO/MPO sensing.
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Cy7-NphS merit fast response time and high sensitivity.
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Cy7-NphS could be used for real-time HClO imaging in living cells.
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Cy7-NphS could respond to MPO activity linearly within the clinical range.
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Cy7-NphS was mitochondria targeted.